With millions of pounds at stake, there’s everything to play for at the King Power Stadium and the selection calls to be made by Solskjaer and Brendan Rodgers will be absolutely crucial.
Sportsmail takes a closer look at some of the dilemmas facing both managers ahead of the season finale.
Will Marcus Rashford start for United after midweek criticism?
United could have made matters easier for themselves if they’d taken all three points at home to West Ham on Wednesday night.
But they turned in a listless and low-energy performance to only draw 1-1, confirming that a lot of their post-restart momentum has now been lost.
Marcus Rashford, Paul Pogba and Bruno Fernandes were among many guilty of under-par performances at Old Trafford.
In the Sky Sports studio, former United defender Patrice Evra singled out Rashford, saying: ‘I’ve not seen any harsh words yet about Rashford. He had a really poor game today.’